Smedpack is a collaborative research project involving a wide consortium of stakeholders: regulators, pharmacies, academia, civil society organisations, the pharmaceutical industry, and logistics and packaging companies. It aims to prevent counterfeit medicines from entering the legal distribution chain, through concepts for secure pharmaceutical packaging. New packaging concepts (e.g., secure seals, unique serial numbers, apps) will make it easier for consumers and supply chain actors to distinguish genuine products from counterfeit. The ambition is to develop industrially realisable solutions that entail new commercial opportunities.