Project

MIROR - Methods in Research on Research in the field of clinical research.

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Uploaded by RRI Tools on 07 February 2018

English

TIME

From 01/03/2016 to 29/02/2020

What is Research on Research?

Research on Research is an emerging new scientific discipline that aims to identify and minimise persistent threats to medical research quality.

Why should we develop Research on Research?

Tens of billions of Euros are spent each year on studies that are redundant, flawed in their design, never published or poorly reported. Further, given current research practices, research claims are more likely to be false than true. The public is the main victim of this waste. If clinical research is not adequately planned, conducted and reported, clinicians are prevented from using effective health interventions in practice and researchers from adequately prioritising future research questions. This situation ultimately has a detrimental impact on patient care. Therefore, reducing waste and increasing value of research represents a major societal challenge.

What is our aim?

Our aim is to create, in Europe, an innovative and ambitious multidisciplinary intersectoral joint doctoral training programme, dedicated to Methods in Research on Research (MiRoR) in the field of clinical research.

Our overarching aim is to train the future generations of top-level scientists in Research on Research and to develop creative solutions to transform clinical research practice and increase its value.

MiRoR is a joint doctoral programme on Methods in Research on Research in clinical research, involving 15 early-stage researchers (ESRs, i.e. PhD students). We will:

  • Prepare students for envisioning the future challenges in clinical research and find innovative solutions to face them,
  • Train students to go well beyond the state-of-the-art in their research,
  • Help students think differently, taking advantage of the multidisciplinary expertise and intercultural diversity of the network,
  • Teach students how to move from research to action and convert knowledge and idea into a product,
  • Help students to develop skills to match the public and private sector needs and create new professional opportunities.

What will MiRoR consider?

To improve the training of students and confront them with diverse situations and research context and methods, we consider clinical research in its complexity. We will tackle:

  • Several steps of a clinical research project (planning, conduct, reporting and peer-review);
  • Various study designs (observational studies, randomised trials, systematic reviews);
  • Various study questions (therapeutic, diagnostic, and prognostic evaluation).

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Individual Research Project

  • ESR 1 - Methods of identifying gaps in clinical research
  • ESR 2 - An alternative approach for planning the research of innovative medical tests
  • ESR 3 - Methods for including participants in core outcome set development
  • ESR 4 - Improving the planning and monitoring of recruitment to clinical trials
  • ESR 5 - Impact of mobilising collective intelligence in clinical research planning
  • ESR 6 - Improving the use and understanding of causal methods in clinical research
  • ESR 7 - Improving the assessment of Risk of Bias in systematic reviews
  • ESR 8 - Estimation of causal effects from observational studies: how results obtained from different causal inference methods can be integrated in a meta-analyses approach.
  • ESR 9 - Use of reporting guidelines as an educational intervention for teaching research methods and writing
  • ESR 10 - Strategies for avoiding “spin” (i.e., distorted reporting) in research reports
  • ESR 11 - Assisted authoring for avoiding inadequate claims in scientific reporting
  • ESR 12 - Text mining for the systematic survey of diagnostic tests in published or unpublished literature
  • ESR 13 - Peer-review content and communication process in a major biomedical journal
  • ESR 14 - Assessing interventions to improve reporting guidelines adherence
  • ESR 15 - Measuring review report quality in health research

 

Beneficiaries
  • University Paris Descartes, France
  • University of Amsterdam, The Netherlands
  • Universitat Politecnica de Catalunya, Spain
  • CNRS (Centre national de la recherche scientifique), France
  • University of Ghent, Belgium
  • University of Liverpool, UK
  • University of Split, Croatia
Partner institutions
  • BioMed Central (BMC)
  • The British Medical Journal (BMJ)
  • Cochrane
  • ECRIN European Clinical research Infrastructure network (ECRIN)
  • University of Oxford, EQUATOR network
  • Ottawa Hospital Research Institute
  • The Meta-Research Innovation Center at Stanford University
  • National Institute for Health and Care Excellence
  • Sideview
  • University of Paris-Saclay

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