This report builds on recent creative thinking about innovation, benefit and risk, drawing on experience and observation. The authors of this report have brought together perspectives from a wide range of disciplines. Our aim is to help policymakers and citizens to make better-informed choices about innovation. In order to do that, we focus on the ways in which risk can be governed most effectively. We invite debate about how the principles outlined in this report should be applied to decisions taken at local, national, European and global scales.