Knowledge for Climate (2007–2014) was a Dutch research programme aimed at developing applied knowledge, through cooperation between the Dutch government, the business community and scientific research institutes, to ensure that long-term decision making considers the impacts of climate change. It focused on a limited number of vulnerable areas, or ‘hotspots’, and regional knowledge programmes using an integrated multi-stakeholder participative approach in three phases: 1) ‘low-hanging fruit’ projects, which were often practical and easily implemented; 2) doctoral projects in science; 3) valorisation and regional adaptation schemes.