Researchers have the opportunity to be part of the Seventh Framework Program, a research programme that promotes excellence and innovation, and which respects freedom of research whilst ensuring the respect of fundamental ethical principles. Ethics must be given the highest priority in EU funded research as an integral part of research, permeating every area of research and it is only by getting the ethics rights that research excellence can be achieved. This publication presents the Ethics Review procedure of the European Commission in details: the objectives, the relevant legislation, the composition of Ethics Review panels. As for methodology, it defines ethical issues – informed consent, data protection and privacy, research on human embryos, animals, dual use and developing countries -, gives practical advice to researchers and explains via case studies. The moral from this publication is: do not forget research ethics.