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CAMARADES: Collaborative Approach to Meta-Analysis and Review of Animal Data from Experimental Studies

Uploaded by RRI Tools on 19 December 2016

CAMARADES now has five global national co-ordinating centres:

  • University of Edinburgh,
  • Florey Institute of Neuroscience & Mental Health,
  • Radboud University Nijmegen Medical Centre,
  • University of California San Francisco 
  • Ottawa Hospital Research Institute.

See the complete list of global collaborators here

Funded by the MRC Trials Methodology Hub, the MS Society, the Scottish Chief Scientist Office and the NC3Rs

The CAMARADES collaboration provides a supporting framework for groups involved in the systematic review and meta-analysis of data from experimental animal studies.

Our interests range from identifying potential sources of bias in animal work; developing recommendations for improvements in the design and reporting of animal studies; developing the meta-analysis methodology the better to apply it to animal studies; through to the selection of candidate stroke drugs for clinical trial.

CAMARADES aims to provide a central focus for data sharing; to act as a resource for those wishing to carry out such reviews; to provide a web based stratified meta-analysis bioinformatics engine (under development!); and to act as a repository for completed reviews.


CAMARADES has two ongoing projects on the impact of reporting guidelines in the pre-clinical literature:

  • IICARus - A randomised controlled trial of an Intervention to Improve Compliance with the ARRIVE guidelines
  • NPQIP - Nature Publication Quality Improvement Project

We would really appreciate your collaboration and support with these studies! The resulting papers will be published in the name the IICARus or NPQIP collaborators

SyRF is the CAMARADES-NC3Rs in vivo systematic review and meta-analysis facility. It aims to provide an easily accessible source of methodological support, mentoring, guidance, educational materials and practical assistance to those wishing to embark on systematic review and meta-analysis of data from in vivo studies


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